Inscinstech Tangential Flow Filtration System

• Filtration Area: 50cm²-0.1m²
• Maximum Feed Pressure: 5bar
• Minimum Recirculating Volume: 20ml
• Process Temperature: 2-50°c
• Feed Pump Flow Rate: 0-700ml/Min
• Retentate Pump Flow Rate: 0-600ml/Min
• Model NO.: Unique AutoTFF075
• Permeate Pump Flow Rate: 0-300ml/Min
• Recirculation Vessel Volume: 1000ml
• Stirring Speed: 0-300rpm
• Specification: LxDxH: 580 x 355 x 640mm
• Trademark: Inscinstech
• Origin: China Suzhou

Product Description

 

Unique AutoTFF™075

 

Unique AutoTFF™075 is a flexible and automated lab scale tangential flow filtration(TFF)system that can be used with hollow fibers or cassette filters for  concentration, diafiltration or clarification of samples. It is widely used in biological product process, such as antibodies, recombinant proteins,  mRNA, nucleic acids, viral vectors, etc. Its flexible configuration allows for manual operation and highly automated process control. Combined  with a comprehensive management system, it is suitable for small-scale process development, process scale up study, and sample preparation.

 

Product Features

• Automatic TMP control, weighing, feeding,  precise control of concentration ratio and  diafiltration volume

   

• Compact design, small recirculation  volume, to meet high concentration  requirements

   

• The User friendly control software offers  easily recipe setup, operation control, data  recording and user management

   

• Optional permeate pumplfor comprihensive  microfiltration processe control

   

• High automation with pre-defined  method modules, recipe and recipe  sequence

   

• Optional conductivity sensor, pH, UV, for  comprehensive process monitoring

   

• Adapt to different type of cassette filters  and hollow fibers

   

Predefined method modules

 

Method Module			Function
Filling			Add a certain amount of liquid to the circulation vessel
Water flux test			Can automatically test water flux based on defined pressure/crossflow conditions
Clarification / Concentration			Concentrate the feed liquid to the defined volume or concentration factor
Diafiltration			Constant volume diafiltration with continuouse feed entill predefined endpoint, eg.  Diltiltration volume, conductivity, pH
Harvest/Drain			Harvest the liquid through the harvesting port or outlet valve
CIP			Used for system cleaning
Flush			Flush the system with water, buffer or other solutions
Pause			System pause

Unique AutoTFF™075  Specification

 

Dimensions(LxDxH,mm)			580 x 355 x 640 (filter holder not included)
Electrical requirements			240VAC, 50-60Hz
Weight			48kg(include 0.1m² filter holder)
Power			150W
System language			English,Chinese
Ambient temperature			2-35°C

 

 

Filtration area				50cm²-0.1m²(The specific filtration area can be varied with different filters)
Maximum feed pressure				5bar
Minimum recirculating volume				20ml
Process temperature				2-50°C
Feed pump flow rate				0-700ml/min
Retentate pump flow rate				0-600ml/min
Permeate pump flow rate				0-300ml/min
Recirculation vessel volume				1000ml
Stirring speed				0-300rpm
Pressure sensor				Detection range: 0-5Bar
Conductivity sensor				Detection range: 0-999.999ms/cm
Temperature sensor				Integrated in conductivity sensor, detection range: 0-99ºC
pH				Detection range: 1-14
Retentate and filtration weighing				0-6kg
Filter holder				1 ABS multifunctional holder for 50cm ² Capsule capsule or hollow fiber filters with a diameter no more than 50mm 1 0.1m ² Stainless steel holder
Tube&Connector				Luer Lock